But a suspicious figure is using both the Jump Force and the Venoms as an attempt to gain a mysterious artifact and merge all worlds into one.
In order to fight back, many heroes are recruited to join the 'Jump Force' under the leadership of Director Glover and his A.I. When the real world collides with many of the Shōnen Jump universes, humanity is invaded by the 'Venoms', an army of mind-controlled villains led by Kane and Galena.